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OutcomesWe considered the following clinical outcomes:

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pandora essence Kubo (Observatorio Astronmico Nacional de Japn, Mitaka, Tokio, Japn); M. J. Michaowski (Instituto de Astronoma, Universidad de Edimburgo, Real Observatorio https://www.jewelleryn394a.top, Edimburgo, Reino Unido); D. OutcomesWe considered the following clinical outcomes: hospital or 30 day mortality (primary outcome), six month mortality, duration of mechanical ventilation, ventilator free days to day 28 or 30, health related quality of life at one year, and treatment failure leading to crossover to the other arm or discontinuation of the study protocol (secondary outcomes). We also considered physiological outcomes measured at 24, 48, and 72 hours after randomisation: oxygenation pandora bracelets, measured by the ratio of partial pressure of arterial oxygen (PaO2) to inspired fraction of oxygen (FiO2) (PaO2/FiO2 ratio); oxygenation index (OI, defined as 100mean airway pressure/(PaO2/FiO2 ratio)); ventilation, measured by partial pressure of carbon dioxide (PaCO2); and mean airway pressure. Finally, we considered adverse events including barotrauma, hypotension, obstruction of endotracheal tube from secretions, and technical complications and equipment failure in patients treated with high frequency oscillation (including unintentional system air leaks and problems with the oscillatory diaphragm, humidifier, and alarm systems).21 42 pandora essence.

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